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Allele : Tg(tetO-SNCA)7Vle transgene insertion 7, Virginia M-Y Lee
Primary Identifier  MGI:5289965 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence Gene  Tg(tetO-SNCA)7Vle
Strain of Origin  Not Specified Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  This transgene consists of the human wild-type alpha-synuclein cDNA under the control of the tetracycline responsive promoter. Alpha-synuclein is expressed only in the presence of the tetracycline transactivator (tTA), expressed from a second transgene; administration of doxycycline inhibits tTA binding to tetO, thus suppressing alpha-synuclein expression.
  • mutations:
  • Insertion
  • synonyms:
  • tetP-WTapha-syn,
  • tetP-WTapha-syn
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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