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Allele : Vim<em2(dre)Bzsh> vimentin; endonuclease-mediated mutation 2, Bin Zhou

Primary Identifier  MGI:6720927 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Recombinase Gene  Vim
Strain of Origin  C57BL/6J Is Recombinase  true
Is Wild Type  false
molecularNote  By genome editing using CRISPR-Cas9 technology, a cDNA containing loxp-stop-loxp-Dre-polyA (LSL-Dre) cassette was inserted into the translation start codon of the Vim gene. To strengthen the stability of the transcripts, the woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) was also included following the Dre signal sequence.
  • mutations:
  • Insertion
  • synonyms:
  • Vim-LSL-Dre,
  • Vim-LSL-Dre
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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1 Driven By

Trail: Allele

2 Publication categories

Trail: Allele