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Protein Coding Gene : Gpt glutamic pyruvic transaminase, soluble

Primary Identifier  MGI:95802 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  76282
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable L-alanine:2-oxoglutarate aminotransferase activity. Predicted to be involved in positive regulation of gluconeogenesis. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human GPT (glutamic--pyruvic transaminase).
PHENOTYPE: Electrophoretic variants are detected in C57BL/6, BALB/c and DBA/2 (a allele); in MA/J and NZB/Bl (b allele). M. m. molossinus and M. m. castaneus have either the b or c allele. In liver, GPT1 activity rises dramatically at 12-19 days to adult levels. [provided by MGI curators]
  • synonyms:
  • Gpt,
  • MGD-MRK-10236,
  • Gpt-1,
  • glutamic pyruvic transaminase 1, soluble,
  • glutamic pyruvic transaminase, soluble,
  • MGI:1923532,
  • Gpt1,
  • ALT,
  • 1300007J06Rik,
  • RIKEN cDNA 2310022B03 gene,
  • MGD-MRK-10237,
  • 2310022B03Rik,
  • RIKEN cDNA 1300007J06 gene,
  • MGI:1915263

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5 Involved In Mutations

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Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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