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Allele : Mmp14<m1Btlr> matrix metallopeptidase 14 (membrane-inserted); mutation 1 Bruce Beutler

Primary Identifier  MGI:3784968 Allele Type  Chemically induced (ENU)
Gene  Mmp14 Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  The mutation is a T-to-C transition at nucleotide position 1642 (Genbank Accession NM_008608) resulting in replacement of serine by proline at amino acid position 422 of the protein (S422P), near the middle of the hemopexin-like domain, which is involved in homodimer formation and mediates association with and cleavage of CD44.
  • mutations:
  • Single point mutation
  • synonyms:
  • cartoon,
  • cartoon
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele