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Allele : Gata1<tm2Sho> GATA binding protein 1; targeted mutation 2, Stuart Orkin

Primary Identifier  MGI:2177586 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gata1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP-flanked neomycin selection cassette replaced the "IT" and DNAseI hypersensitive region of the promoter. RT-PCR experiments demonstrated that this mutation resulted in the loss of expression in megakaryocytes and fetal liver but not in erythroid cells.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • neo deltaHS,
  • GATA-1<low>,
  • neodeltaHS,
  • GATA-1<low>,
  • neodeltaHS,
  • neo deltaHS
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

24 Publication categories

Trail: Allele