| Primary Identifier | IPR013558 | Type | Domain |
| Short Name | CTNNB1-bd_N |
| description | This region tends to appear at the N terminus of proteins also containing DNA-binding HMG (high mobility group) boxes () and appears to bind the armadillo repeat of CTNNB1 (beta-catenin), forming a stable complex. Signalling by Wnt through TCF/LCF is involved in developmental patterning, induction of neural tissues, cell fate decisions and stem cell differentiation []. Isoforms of HMG T-cell factors lacking the N-terminal CTNNB1-binding domain cannot fulfil their role as transcriptional activators in T-cell differentiation [, ]. |
