| Primary Identifier | MGI:1925226 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 77976 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable p53 binding activity and protein serine/threonine kinase activity. Predicted to be involved in regulation of cell adhesion and regulation of cellular senescence. Predicted to act upstream of or within DNA damage response; cell adhesion; and phosphorylation. Predicted to be located in cytoplasm; microtubule cytoskeleton; and nuclear lumen. Is expressed in several structures, including alimentary system; cardiovascular system; embryo ectoderm; nervous system; and renal cortex. Human ortholog(s) of this gene implicated in uterine fibroid. Orthologous to human NUAK1 (NUAK family kinase 1). PHENOTYPE: Mice homozygous for a targeted disruption of this gene die perinatally displaying omphalocele with a failure in closure of the secondary body wall. No gross morphological defects are detected in brain. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
