|  Help  |  About  |  Contact Us

Protein Coding Gene : Mettl2 methyltransferase 2, methylcytidine

Primary Identifier  MGI:1289171 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  52686
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables tRNA (cytidine-3-)-methyltransferase activity. Involved in tRNA methylation. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; heart; respiratory system; and sensory organ. Orthologous to several human genes including METTL2A (methyltransferase 2A, tRNA N3-cytidine).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced 3-methylcytidine (m3C) methyltransferases modification of tRNA. [provided by MGI curators]
  • synonyms:
  • Mettl2,
  • 2810438F06Rik,
  • methyltransferase 2, methylcytidine,
  • MGI:1920002,
  • C130031G21Rik,
  • RIKEN cDNA 2810438F06 gene,
  • MGI:2442741,
  • MGI:2144544,
  • RIKEN cDNA C130031G21 gene,
  • DNA segment, Chr 11, ERATO Doi 768, expressed,
  • AW493404,
  • expressed sequence AW493404,
  • PSENIP1,
  • D11Ertd768e

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

4 Driver For