| First Author | Hayes CE | Year | 1984 |
| Journal | Science | Volume | 223 |
| Issue | 4636 | Pages | 559-63 |
| PubMed ID | 6607530 | Mgi Jnum | J:7323 |
| Mgi Id | MGI:55794 | Doi | 10.1126/science.6607530 |
| Citation | Hayes CE, et al. (1984) Chromosome 4 Jt gene controls murine T cell surface I-J expression. Science 223(4636):559-63 |
| abstractText | Data are presented suggesting a resolution to the paradox concerning the murine response subregion I-J, which encodes a suppressor T cell marker. The controversy arose when sequences corresponding to I-J DNA were not found in the central immune response region described by immunogeneticists. New evidence is presented that T cell surface I-J expression results from the action of at least two complementing genes. One gene is within the H-2 region on chromosome 17; the second gene, termed Jt, is on chromosome 4. The two recombinant mouse strains B10.A(3R) and B10.A(5R) originally used to define the I-J subregion apparently differ not within the H-2 region but elsewhere. |
