Primary Identifier | MGI:4452369 | Allele Type | Targeted |
Gene | Igh | Transmission | Germline |
Strain of Origin | B6(Cg)-Tyr<c-2J> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | An frt-flanked neo cassette with 5' loxP and I-SceI site was inserted into the 3' Ighg1 switch region. Flp mediated recombination removed the neo cassette leaving the single loxP site. ES cells originally used to create this allele also contained Ightm3Mnz 96 kb upstream. |