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Type  function Description  Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis (By similarity). Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis (By similarity). Regulates ER stress-induced neuronal apoptosis (PubMed:21159964, PubMed:22761832).
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