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Protein Coding Gene : Irs3 insulin receptor substrate 3

Primary Identifier  MGI:1194882 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  16369
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables phosphatidylinositol 3-kinase activator activity and phosphatidylinositol 3-kinase binding activity. Involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in plasma membrane. Is expressed in several structures, including heart; liver; lung; metanephros; and spleen. Orthologous to human IRS3P (insulin receptor substrate 3, pseudogene).
PHENOTYPE: Mice homozygous for a targeted mutation are viable, fertile and display no detectable abnormalities in growth or glucose homeostasis. [provided by MGI curators]
  • synonyms:
  • AA408304,
  • MGI:2140734,
  • Irs3,
  • expressed sequence AA408304,
  • insulin receptor substrate 3

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For