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Protein Coding Gene : Nudt21 nudix hydrolase 21
Primary Identifier  MGI:1915469 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  68219
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chromatin binding activity. Involved in positive regulation of pro-B cell differentiation; positive regulation of stem cell differentiation; and post-transcriptional regulation of gene expression. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; early embryo; respiratory system; and sensory organ. Orthologous to human NUDT21 (nudix hydrolase 21).
PHENOTYPE: Mice homozygous for a conditional allele activated in Col1a1-expressing cells exhibit increased bleomycin-induced fibrosis and inflammation in the lungs. [provided by MGI curators]
  • synonyms:
  • MGI:1917892,
  • RIKEN cDNA 5730530J16 gene,
  • nudix (nucleoside diphosphate linked moiety X)-type motif 21,
  • AU014860,
  • nudix hydrolase 21,
  • 5730530J16Rik,
  • AW549947,
  • Nudt21,
  • 3110048P04Rik,
  • expressed sequence AU014860,
  • 25kDa,
  • cleavage and polyadenylation specific factor 5,
  • Cpsf5,
  • expressed sequence AW549947,
  • MGI:2142804,
  • MGI:2142673,
  • RIKEN cDNA 3110048P04 gene
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