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Allele : Camk2a<tm2Yelg> calcium/calmodulin-dependent protein kinase II alpha; targeted mutation 2, Ype Elgersma

Primary Identifier  MGI:7254975 Allele Type  Targeted
Attribute String  Conditional ready, Null/knockout, Reporter Gene  Camk2a
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing Camk2a-exon2 fused to tdTomato, followed by the woodchuck hepatitis virus post-transcriptional regulatory element (WPRE), flanked by LoxP sites, and a neomycin cassette for positive selection, flanked by Frt sites was inserted upstream of Camk2a exon2. This results in a KO first mutant mouse line expressing tdTomato from the endogenous Camk2a promoter. Crossing this line with a cre line restores CAKM2A expression.
  • mutations:
  • Insertion
  • synonyms:
  • Camk2a-LSL,
  • Camk2a-LSL
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele