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Allele : Aicda<tm4.1Mnz> activation-induced cytidine deaminase; targeted mutation 4.1, Michel C Nussenzweig

Primary Identifier  MGI:3839323 Allele Type  Targeted
Gene  Aicda Transmission  Germline
Strain of Origin  B6(Cg)-Tyr<c-2J>/J Is Recombinase  false
Is Wild Type  false
molecularNote  Threonine 140 of Exon 3 was mutated to alanine (by introducing an A95G base pair change) and a loxP-flanked neomycin resistance cassette was placed in intron 2. A B6(Cg)-Tyrc-2J/J-derived embryonic stem cell line was used to create the mutation. The neomycin cassette was excised with Cre, leaving a single loxP site.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • AID T140A,
  • AID T140A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele