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Allele : Igf2<tm1Snha> insulin-like growth factor 2; targeted mutation 1, Sylvie N Hardouin

Primary Identifier  MGI:4880744 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout, Reporter Gene  Igf2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Alternative exon 1, including the second alternative promoter P2 upstream of it (Rr145), was replaced with a lacZ-neo cassette via homologous recombination. Real-time PCR analysis showed reduced total transcripts throughout development. However, no reduction in total protein level was detected during development.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Igf2-P2<->,
  • Igf2-P2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele