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Allele : Tmem263<em1Gww> transmembrane protein 263; endonuclease-mediated mutation 1, Guang William Wong
Primary Identifier  MGI:7612228 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tmem263
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology using gRNAs 5’-CTATCATATGTCTCTCATTAG-3’ AND 5’-GCCACTGGCATCATATGCTG-3’ deleted exon 3 that encodes approximately 81% of the full-length protein. qPCR confirmed the absence of transcript in the liver and hypothalamus of homozygotes.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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