| Primary Identifier | MGI:1309511 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 12545 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including cell cycle phase transition; double-strand break repair via break-induced replication; and positive regulation of cell cycle process. Predicted to act upstream of or within cell division and phosphorylation. Predicted to be located in intercellular bridge; mitotic spindle; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including gut; hemolymphoid system gland; musculature; nervous system; and sensory organ. Orthologous to human CDC7 (cell division cycle 7). PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality between E3.5-E6.5. In conjunction with a Trp53-null allele, double homozygous mutant embryos survive up to E8.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
