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Protein Coding Gene : Pdzk1 PDZ domain containing 1
Primary Identifier  MGI:1928901 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  59020
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable PDZ domain binding activity; protein-membrane adaptor activity; and scavenger receptor binding activity. Involved in positive regulation of protein targeting to membrane; protein localization to plasma membrane; and regulation of monoatomic anion transport. Acts upstream of or within in utero embryonic development. Located in brush border membrane. Is expressed in several structures, including genitourinary system; liver; lung; thymus; and white fat. Orthologous to several human genes including PDZK1 (PDZ domain containing 1).
PHENOTYPE: Homozygous mutation of this gene results in increased serum cholesterol levels. [provided by MGI curators]
  • synonyms:
  • 4921513F16Rik,
  • MGI:2139848,
  • expressed sequence AI314638,
  • mPDZK1,
  • RIKEN cDNA 2610507N21 gene,
  • MGI:1918104,
  • expressed sequence AI267131,
  • D3Ertd537e,
  • RIKEN cDNA 1700023D20 gene,
  • MGI:2139665,
  • 2610507N21Rik,
  • AI314638,
  • MGI:1919393,
  • Pdzk1,
  • MGI:1919470,
  • 1700023D20Rik,
  • AL022680,
  • MGI:2139658,
  • AI267131,
  • RIKEN cDNA 4921513F16 gene,
  • PDZ domain containing 1,
  • Nherf3,
  • expressed sequence AL022680,
  • DNA segment, Chr 3, ERATO Doi 537, expressed,
  • MGI:1277210
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Trail: ProteinCodingGene

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