Primary Identifier | IPR034369 | Type | Domain |
Short Name | SCAF4_RRM |
description | This entry represents the RNA recognition motif(RRM) of SCAF4 (also known as Splicing factor, arginine/serine-rich 15) that belongs to a new class of SCAFs (SR-like CTD-associated factors). Although its biological function remains unclear, SCAF4 shows high sequence similarity to SCAF8 that interacts specifically with a highly serine-phosphorylated form of the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II (pol II) and may play a direct role in coupling with both, transcription and pre-mRNA processing, processes []. SCAF4 and SCAF8 both contain a conserved N-terminal CTD-interacting domain (CID), an atypical RNA recognition motif (RRM) and serine/arginine-rich motifs. |