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Comment :

Type  MGI:General Description  electrogram duration (EGD) during programmed electrical stimulation parallels (PES) arrhythmic tendencies unlike in wild-type mice, propranolol fails to suppress arrhythmias following treatment with isoproterenol isoproterenol does not affect arrhythmia status during PES whereas in wild-type mice it induces arrhythmic effects mexiletine suppresses arrhythmias in 4 of 5 mice without effecting EGD