| Primary Identifier | MGI:1919995 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 72745 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in regulation of cardiac muscle cell action potential and regulation of heart rate. Predicted to be located in plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human TMEM161B (transmembrane protein 161B). PHENOTYPE: Homozygous knockout mice exhibit lethality before weaning and leads to holoprosencephaly and craniofacial, cerebral cortex stratification and retina pigment epithelium abnormalities in embryos. Heterozygous KO leads to decreased circulating serum albumin and total protein levels and bone mineral content, lower lean body mass and higher total body fat amount. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
