Primary Identifier | MGI:7316455 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tcfl5 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The loxP flanked exon 4 was removed via cre-mediated recombination in the germline. Homozygous mutant testes lack the full-length transcript but show the presence of aberrant transcripts. Western blot analysis demonstrated the absence of protein expression in testes. Immunofluorescence analysis confirmed the absence of protein in spermatocytes. |