| Primary Identifier | MGI:3871218 | Allele Type | Gene trapped |
| Attribute String | Null/knockout, Reporter | Gene | Lemd2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Sanger Inst. Gene Trap Res. |
| molecularNote | The gene trap introduced a sequence between exons 3 and 4 of the gene that contains a splice acceptor site (SA), a cDNA encoding the beta-galactosidase reporter linked to neomycin (geo), and a SV40 cleavage/polyadenylation site (pA). While the mutant allele is predicted to generate an ~175-kDa fusion protein, a full length expression product was not detected. Smaller presumptive degredation products were seen on Western blot, albeit at reduced levels. |
