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Protein Coding Gene : Kif22 kinesin family member 22

Primary Identifier  MGI:109233 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  110033
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement; mitotic metaphase chromosome alignment; and sister chromatid cohesion. Located in spindle. Part of chromatin. Is expressed in cerebral cortex ventricular layer; cortical plate; and inner cell mass. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 2. Orthologous to human KIF22 (kinesin family member 22).
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality prior to implantation due to defective meiosis II and early embryo mitosis. [provided by MGI curators]
  • synonyms:
  • C81217,
  • Kif22,
  • Kif22a,
  • MGI:2142351,
  • Kid,
  • expressed sequence AU021460,
  • kinesin family member 22A,
  • expressed sequence C81217,
  • AU021460,
  • kinesin family member 22,
  • MGI:2142138,
  • MGD-MRK-38277

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

5 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For