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Protein Coding Gene : Dact2 dishevelled-binding antagonist of beta-catenin 2

Primary Identifier  MGI:1920347 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  240025
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables several functions, including beta-catenin binding activity; delta-catenin binding activity; and protein kinase C binding activity. Involved in several processes, including epithelial cell morphogenesis; inner medullary collecting duct development; and negative regulation of nodal signaling pathway. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and umbilical vein. Orthologous to human DACT2 (dishevelled binding antagonist of beta catenin 2).
PHENOTYPE: Mice homozygous for a knock-out allele develop normally but display enhanced keratinocyte migration and accelerated re-epithelialization during cutaneous wound healing. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2900084M21 gene,
  • Frd2,
  • 2900084M21Rik,
  • Dpr2,
  • dapper2,
  • dishevelled-binding antagonist of beta-catenin 2,
  • Dact2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

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0 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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1 Driver For