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Protein Coding Gene : Irgc immunity related GTPase cinema
Primary Identifier  MGI:2685948 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  210145
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable GTPase activity. Predicted to be located in membrane. Orthologous to human IRGC (immunity related GTPase cinema).
PHENOTYPE: Mice homozygous for a null allele exhibit reduced male fertility associated with short sperm flagellum, decreased sperm progressive motility, impaired sperm penetration of zona pellucida, and disorganized sperm fibrous sheath morphology. [provided by MGI curators]
  • synonyms:
  • immunity related GTPase cinema,
  • gene model 474, (NCBI),
  • immunity related GTPase cinema 1,
  • Irgc1,
  • RIKEN cDNA F630044M05 gene,
  • Iigp5,
  • Gm474,
  • immunity-related GTPase family, cinema 1,
  • interferon inducible GTPase family member 5,
  • Irgc,
  • LOC210145,
  • MGI:2685320,
  • F630044M05Rik,
  • LOC381989,
  • gene model 1102, (NCBI),
  • Gm1102
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