| Primary Identifier | MGI:2153045 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 140579 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable receptor tyrosine kinase binding activity. Predicted to be involved in actin filament organization and cell chemotaxis. Predicted to act upstream of or within apoptotic process and phagocytosis. Predicted to be located in cytosol and membrane. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; liver; nervous system; and retina. Orthologous to human ELMO2 (engulfment and cell motility 2). PHENOTYPE: Mice homozygous for a null allele exhibit no gross abnormalities with normal muscle morphology and regeneration. Mice homozygous for an allele lacking the inhibiting domain exhibit enhanced skeletal muscle regeneration. Mice homozygous for an allele lacking the RAS-binding domain exhibit impaired skeletal muscle regeneration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
