| Type | MGI:General | Description | following transverse aorta constriction mice develop marked left ventricular dilatation with a significant decrease in fractional shortening resulting in heart failure compared to wild-type controls that develop adaptive cardiac hypertrophy with moderate left ventricular dilation cardiomyocyte enlargement following transverse aorta constriction is more severe than in controls more than 70% of mice die by 140 days post transverse aorta constriction compared to only 20% of controls |
