| Primary Identifier | MGI:1923356 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 277250 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including chromatin DNA binding activity; histone H3K9 demethylase activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleoplasm. Predicted to be part of chromatin and histone deacetylase complex. Is expressed in several structures, including central nervous system; early conceptus; oocyte; and retina nuclear layer. Orthologous to human KDM3B (lysine demethylase 3B). PHENOTYPE: Mice homozygous for a knock-out allele show partial postnatal lethality, stunted postnatal growth, reduced serum IGF-1 and estradiol levels, prolonged estrous cycles, decreased ovulation rate and fertilization frequency, abnormal decidualization and embryo implantation, and female infertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
