| Primary Identifier | MGI:1316740 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 17450 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable zinc ion binding activity. Involved in negative regulation of gene expression and spermatogenesis. Acts upstream of or within behavioral fear response; regulation of gene expression; and retrotransposon silencing by heterochromatin formation. Is active in male germ cell nucleus. Is expressed in esophagus; head mesenchyme; musculoskeletal system; sensory organ; and testis. Used to study melancholic depression. Orthologous to human MORC1 (MORC family CW-type zinc finger 1). PHENOTYPE: Inactivation of this locus results in small testes and male sterility, the latter owing to meiotic arrest. Mutant females exhibited histologically normal ovaries and were fertile. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
