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Protein Domain : Parvovirus non-structural protein 1, helicase domain

Primary Identifier  IPR001257 Type  Domain
Short Name  Parvovirus_NS1_helicase
description  Parvoviruses are some of the smallest viruses containing linear, non-segmented single-stranded DNA genomes, with an average genome size of 5000 nucleotides. Parvoviruses have been described that infect a wide range of invertebrates and vertebrates and are well known for causing enteric disease in mammals. Genomes contain two large ORFs: NS1 and VP1; other ORFs are found in some sub-types and different gene products can arise from splice variants and the use of different start codons [, ].This entry represents the helicase domain of the Parvovirus NS1 protein; which is required for viral DNA replication []. This domain contains the ATP/GTP-binding site motif A (P-loop). Parvoviral NS1 also regulates host gene expression through histone acetylation [].

0 Child Features

1 Parent Features

0 Protein Domain Regions