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Comment :

Type  MGI:General Description  mice have mild but significant impairment in spatial learning and memory in the Morris water maze paradigm, mutants and wild-type mice show improvements in performance for the initial 7 days of training, but for the last 3-5 days, mutant performance plateaus while control mice continue to improve in finding the hidden platform in probe trials, mutants diplay fewer crossings of the target quadrant after 10 days of training compared to wild-type mice similar results are obtained when platform position is changed and test is repeated