Primary Identifier | IPR042341 | Type | Family |
Short Name | CD19 |
description | CD19 is a component of a cell surface receptor complex that play critical roles as regulators of B cell responses to a variety of stimuli, influencing cell activation, differentiation, and survival [].Mutations in the CD19 gene cause immunodeficiency, common variable, 3 (CVID3), a primary immunodeficiency characterised by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen []. |