Primary Identifier | MGI:4453212 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Lrp5 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Glycine 170 of the targeted gene was converted to valine (equivalent to the human G171V missense mutation) via site-directed mutagenesis. Cre mediated recombination removed the floxed neo cassette. |