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Protein Coding Gene : Insc INSC spindle orientation adaptor protein

Primary Identifier  MGI:1917942 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  233752
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable cytoskeletal anchor activity and protein domain specific binding activity. Acts upstream of or within establishment of mitotic spindle orientation and lung epithelial cell differentiation. Located in apical part of cell. Is expressed in bone; lung epithelium; metanephros; and nervous system. Orthologous to human INSC (INSC spindle orientation adaptor protein).
PHENOTYPE: Homozygous inactivation of this gene leads to abnormal cochlear hair cell morphology. [provided by MGI curators]
  • synonyms:
  • Inscuteable,
  • 3830422K02Rik,
  • RIKEN cDNA 3830422K02 gene,
  • Insc,
  • INSC spindle orientation adaptor protein

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For