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Publication : Precision and diversity in an odor map on the olfactory bulb.

First Author  Soucy ER Year  2009
Journal  Nat Neurosci Volume  12
Issue  2 Pages  210-20
PubMed ID  19151709 Mgi Jnum  J:161266
Mgi Id  MGI:4457856 Doi  10.1038/nn.2262
Citation  Soucy ER, et al. (2009) Precision and diversity in an odor map on the olfactory bulb. Nat Neurosci 12(2):210-20
abstractText  We explored the map of odor space created by glomeruli on the olfactory bulb of both rat and mouse. Identified glomeruli could be matched across animals by their response profile to hundreds of odors. Their layout in different individuals varied by only approximately 1 glomerular spacing, corresponding to a precision of 1 part in 1,000. Across species, mouse and rat share many glomeruli with apparently identical odor tuning, arranged in a similar layout. In mapping the position of a glomerulus to its odor tuning, we found only a coarse relationship with a precision of approximately 5 spacings. No chemotopic order was apparent on a finer scale and nearby glomeruli were almost as diverse in their odor sensitivity as distant ones. This local diversity of sensory tuning stands in marked distinction from other brain maps. Given the reliable placement of the glomeruli, it represents a feature, not a flaw, of the olfactory bulb.
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