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Publication : Absence of subcommissural organ in the cerebral aqueduct of congenital hydrocephalus spontaneously occurring in MT/HokIdr mice.

First Author  Takeuchi IK Year  1987
Journal  Acta Neuropathol Volume  73
Issue  4 Pages  320-2
PubMed ID  3618124 Mgi Jnum  J:27127
Mgi Id  MGI:74545 Doi  10.1007/BF00688253
Citation  Takeuchi IK, et al. (1987) Absence of subcommissural organ in the cerebral aqueduct of congenital hydrocephalus spontaneously occurring in MT/HokIdr mice. Acta Neuropathol (Berl) 73(4):320-2
abstractText  The midbrains of pups with congenital hydrocephalus spontaneously occurring in MT/HokIdr mice were histologically examined. The subcommissural organ (SCO) and the posterior commissure were completely absent in the hydrocephalic brain. The cerebral aqueduct in the hydrocephalic brain was never completely stenosed, though it was somewhat narrowed in its middle region as compared with that in the normal brain. A possible interrelationship between an absence of SCO and a cause of congenital hydrocephalus is discussed.
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