First Author | Chattopadhyay S | Year | 2014 |
Journal | Mol Cell | Volume | 54 |
Issue | 2 | Pages | 210-1 |
PubMed ID | 24766884 | Mgi Jnum | J:214766 |
Mgi Id | MGI:5603979 | Doi | 10.1016/j.molcel.2014.04.008 |
Citation | Chattopadhyay S, et al. (2014) Meet the terminator: The phosphatase PP2A puts brakes on IRF-3 activation. Mol Cell 54(2):210-1 |
abstractText | Cellular interferon response to microbial infection is transient. In a recent paper in Immunity, Long et al. (2014) identify protein phosphatase 2A (PP2A) as a deactivator of phospho-interferon regulatory factor 3, the key transcription factor for interferon synthesis, thus providing one basis for the observed transiency. |