Primary Identifier | MGI:1913404 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 66154 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable identical protein binding activity. Acts upstream of or within several processes, including erythrocyte differentiation; mitochondrial transport; and regulation of heme biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including central nervous system; hemolymphoid system; salivary gland primordium; sensory organ; and skeletal muscle. Orthologous to several human genes including TMEM14C (transmembrane protein 14C). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit porphyrin accumulation in fetal liver, erythroid maturation arrest, and embryonic lethality due to severe anemia. [provided by MGI curators] |