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Protein Coding Gene : Glp1r glucagon-like peptide 1 receptor

Primary Identifier  MGI:99571 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  14652
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable glucagon receptor activity; glucagon-like peptide 1 receptor activity; and peptide hormone binding activity. Involved in several processes, including learning or memory; positive regulation of blood pressure; and response to psychosocial stress. Acts upstream of or within with a positive effect on hormone secretion. Acts upstream of or within post-translational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; liver; and lung. Orthologous to human GLP1R (glucagon like peptide 1 receptor).
PHENOTYPE: Glucose tolerance and pancreatic secretion is impaired in homozygous null mice. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-16352,
  • Glp1r,
  • GLP-1R,
  • glucagon-like peptide 1 receptor,
  • GLP1Rc

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

4 Driver For