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Protein Coding Gene : Sct secretin

Primary Identifier  MGI:99466 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  20287
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G protein-coupled receptor binding activity and digestive hormone activity. Involved in several processes, including diet induced thermogenesis; hippocampus development; and regulation of appetite. Acts upstream of or within several processes, including dentate gyrus development; neuronal stem cell population maintenance; and visual learning. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; ectoplacental cone; gut; metanephros; and visceral pericardium. Orthologous to human SCT (secretin).
PHENOTYPE: Mice homozygous for a null allele display impaired hippocampal synaptic function. Mice homozygous for a different knock-out allele fail exhibit increased water concsumption of vasopressin serum levels in response to ANGII treatment. [provided by MGI curators]
  • synonyms:
  • Sct,
  • secretin,
  • MGD-MRK-16237

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For