| Primary Identifier | MGI:2685918 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 381810 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable G protein-coupled receptor activity. Acts upstream of or within behavioral response to pain. Predicted to be located in plasma membrane. Is expressed in several structures, including future brain; genitourinary system; gut; immune system; and nervous system. Orthologous to human LPAR5 (lysophosphatidic acid receptor 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit resistance to neuropathic pain and myelin sheath alterations. Mice homozygous for a different targeted allele exhibit decreased nociception sensitivity, decreased anxiety-related response and enhanced coordination and spatial learning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
