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Allele : Ripk1<tm2.1Vmd> receptor (TNFRSF)-interacting serine-threonine kinase 1; targeted mutation 2.1, Vishva M Dixit
Primary Identifier  MGI:6356681 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Ripk1
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence 5'-ATTCAGATTGGA-3', encoding RIP homotypic interaction motif (RHIM) residues IQIG, was replaced with 5'-GCTGCGGCTGCA-3', coding for AAAA. An FRT site flanked neomycin selection cassette inserted into intron 9 at position chr13:34,029,090 (GRCm38/mm10 assembly) was deleted from the targeted embryonic stem cells before microinjection.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Ripk1<RHIM>,
  • Ripk1<RHIM>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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