| Primary Identifier | MGI:107572 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 11798 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; enzyme binding activity; and scaffold protein binding activity. Involved in regulation of apoptosis involved in tissue homeostasis. Acts upstream of or within negative regulation of apoptotic process and neuron apoptotic process. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to several human genes including XIAP (X-linked inhibitor of apoptosis). PHENOTYPE: Homozygous null mutants are indistinguishable from normal littermates, but increased levels of protein from other Birc gene family members suggest a compensatory mechanism in the absence of the Birc4 gene's product. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
