Primary Identifier | MGI:3581819 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(GFAP)10Mes |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene consists of a 17.5 kb fragment of DNA extending about 6 kb upstream to 1.5 kb downstream of the human GFAP gene, including regulatory elements sufficient to direct astrocyte-specific expression. Five lines were established 2 of which had high levels of expression in at least some mice (73.1 uniformly high expression and 73.7 about 20% with high expression). Line 73.7 was given a strain designation TgN(GFAP)Mes10. This is the representative record for both high expressing lines. |