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Protein Coding Gene : H2bc21 H2B clustered histone 21

Primary Identifier  MGI:2448415 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  319190
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in defense response to other organism; killing of cells of another organism; and negative regulation of tumor necrosis factor-mediated signaling pathway. Predicted to be located in cytosol; extracellular space; and nucleoplasm. Predicted to be part of CENP-A containing nucleosome. Predicted to colocalize with plasma membrane. Is expressed in cerebral cortex ventricular layer; olfactory epithelium; and vomeronasal organ. Orthologous to human H2BC11 (H2B clustered histone 11).
PHENOTYPE: Mice homozygous for a null allele exhibit impaired olfactory function and an increased lifespan of mature olfactory sensory neurons associated with decreased neuron apoptosis. [provided by MGI curators]
  • synonyms:
  • AV127319,
  • H2B clustered histone 21,
  • MGI:2139936,
  • T25626,
  • expressed sequence AV127319,
  • expressed sequence T25626,
  • Hist2h2be,
  • MGI:2140111,
  • histone cluster 2, H2be,
  • H2bc21

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

49 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For