| Primary Identifier | MGI:1915387 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 68137 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable KDEL sequence binding activity. Acts upstream of or within T cell apoptotic process and T cell differentiation. Located in cis-Golgi network and endoplasmic reticulum. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1). PHENOTYPE: Mice homozygous for an ENU-induced single point mutation display thymus hypoplasia and a reduction in CD4+ as well as CD8+ T cell numbers. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
