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Protein Coding Gene : Cd3g CD3 antigen, gamma polypeptide

Primary Identifier  MGI:88333 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  12502
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity and transmembrane signaling receptor activity. Predicted to be involved in several processes, including positive thymic T cell selection; protein transport; and regulation of lymphocyte apoptotic process. Predicted to act upstream of or within adaptive immune response. Part of alpha-beta T cell receptor complex. Is expressed in epidermis and lung. Human ortholog(s) of this gene implicated in immunodeficiency 17. Orthologous to human CD3G (CD3 gamma subunit of T-cell receptor complex).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased thymocyte number and T cell response. [provided by MGI curators]
  • synonyms:
  • CD3 antigen, gamma polypeptide,
  • MGD-MRK-1854,
  • T3-gamma chain,
  • Ctg-3,
  • MGD-MRK-14698,
  • Cd3g,
  • MGD-MRK-2212,
  • T3g,
  • MGD-MRK-2213,
  • Ctg3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

19 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For