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Protein Coding Gene : Nr1i2 nuclear receptor subfamily 1, group I, member 2

Primary Identifier  MGI:1337040 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  18171
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor binding activity. Acts upstream of or within positive regulation of gene expression. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; ear; genitourinary system; liver; and nervous system. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2).
PHENOTYPE: Mice homozygous for a targeted null mutation are viable and fertile but exhibit specific loss of xenoregulation of CYP3A11. [provided by MGI curators]
  • synonyms:
  • SXR,
  • PXR,
  • PXR.1,
  • mPXR,
  • Pregnane X receptor,
  • Nr1i2,
  • PXR.2,
  • nuclear receptor subfamily 1, group I, member 2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For